Sentences with phrase «acid receptor»
The phrase "acid receptor" refers to a biological structure or molecule in our body that is specifically designed to detect and respond to acids. Full definition
These breaks help to ensure effectiveness and maintain amino acid receptor site efficiency.
healingedge.net
Oral administration of a retinoic acid receptor antagonist reversibly inhibits spermatogenesis in mice.
GPR120 is an omega - 3 fatty acid receptor mediating potent anti-inflammatory and insulin - sensitizing effects
Prolonged oral administration of a pan-retinoic acid receptor antagonist inhibits spermatogenesis in mice with a rapid recovery and changes in the expression of influx and efflux transporters.
Like different picks in a locksmith's tool, the 17 known subtypes of hemagglutinin, a surface protein on influenza strains, match different sialic acid receptors on a host cell.
The study is important because it links diet to changes in the gut microbiota as well as bile acid profile, opening the possibility that probiotics and bile acid receptor agonists may be useful for the prevention and treatment of hepatic inflammation and progression into advanced liver diseases such as cancer.
The modified nanohybrids with folic acid are mostly accumulated in cancer cells, because they have an increased number of folic acid receptors, so the concentration grows thousand times higher than in healthy cells.
Alterations in Retinoic Acid Receptors in Non-Small Cell Lung Cancer and Their Clinical Implications
These are structurally related, with less than 20 % sequence identity, to other excitatory amino acid receptor subunits, including the NMDA receptor subunit NMDAR1 (NR1).
Chen's team also discovered the body clock receptor that Nobiletin binds to — retinoid acid receptor - related orphan receptors (RORs).
The study shows that activating the bile acid receptor TGR5 with molecules that mimic the action of bile acids (so called «mimetics») induces a remodeling of white fat cells into beige fat cells.
Wilson's laboratory used X-ray crystallography to determine the atomic structures of the H7N9 hemagglutinin protein bound to these sialic acid receptor molecules.
Male sterility in mice lacking retinoic acid receptor α involves specific abnormalities in spermiogenesis
A Biomarker - Directed Phase 2 Trial of SY - 1425, a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Several class C G - protein - coupled receptors (GPRs) have been identified as amino acid receptors [31,32].
His group identified the nature of the jasmonic acid receptor and how it regulates gene expression.
Working with prostate cell cultures, Meier and two students, Ze Liu and Mandi Hopkins, found the fatty acids bind to a receptor called FFA4, for «free fatty acid receptor 4.»
«Adding retinoids calls away retinoic acid receptors, which are then unable to aid transcription of the gene,» Fettig says.
These conjugates were injected i.v. into immunodeficient mice bearing human KB tumors that overexpress the folic acid receptor.
«The cells with 2,3 - sialic acid receptors have been associated with the bronchial mucins,» Tumpey told New Scientist.
Moreover, liver inflammation was most pronounced in Western diet - fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.
«L - Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets.»
Mice treated with a drug that blocks what's known as the retinoic acid receptor have defective sperm that don't line up (right, arrows).
The acid binds to the retinoic acid receptor, which is found in cells throughout the body.
Her group is also collaborating with a team of medicinal chemists to look for compounds that target only the alpha version of the retinoic acid receptor.
In the 1990s, scientists reported that when they disrupted the gene for one version of the retinoic acid receptor, referred to as alpha, in mice, «the animals are fine, but the males are sterile,» says geneticist Debra Wolgemuth of Columbia University Medical Center.
Retinoic acid receptors are one of these cofactors, recruiting additional proteins to open DNA.
When retinoic acid is added however, these gatekeepers, including retinoic acid receptors, are called away leaving progesterone receptors without assistance in pulling open the heavy doors of DNA and causing shutdown of CK5 expression.
Palovarotene is a retinoic acid receptor (RAR) agonist, a molecule that binds a cell membrane receptor to trigger molecular events that regulate cell function.
They are now investigating hybrid compounds that incorporate scaffolds and structural features from several other compounds known to interact with the retinoic acid receptor.
Unfortunately, both types of modifications also reduced the specificity of the compounds for the intended retinoic acid receptor - α target.
That means the compound not only interacts with the retinoic acid receptor - α, which is involved in male fertility, but also with two other retinoic acid receptors that are unrelated to fertility.
To find out if that happens in the face, a team led by developmental biologist Jill Helms of the University of California, San Francisco, applied a molecule that blocks the retinoic acid receptor to the head region of developing chicks.
It was originally thought that ATRA was successfully treating APL by inducing cell differentiation, causing cancer cells to change into normal cells by activating the cellular retinoic acid receptors.
The predominant function of retinoids in vivo involves their binding as ligands to retinoic acid receptor (RAR) or retinoid X receptor transcription factors (4).
Upregulation of retinoic acid receptor - ß reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis.
ATRA regulates gene expression by activating the retinoic acid receptor.
The retinoic acid receptor - α modulators ATRA and Ro415253 reciprocally regulate human IL - 5 + Th2 cell proliferation and cytokine expression.
Butyrate and propionate protect against diet - induced obesity and regulate gut hormones via free fatty acid receptor 3 - independent mechanisms
Improved glucose control and reduced body fat mass in free fatty acid receptor 2 — deficient mice fed a high - fat diet.
Butyrate and Propionate Protect against Diet - Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3 - Independent Mechanisms.