Sentences with phrase «active site»

The liver is the most active site of lipid synthesis.

Sometimes a smaller site that could be considered a niche site can serve as a lead in to one of the larger and more active sites.

However, there are many members who have complained that the last login of many of the men in the site is quite old, so it is not a very active site.

If active sites work slowly or fail quickly, the result is higher costs and lower production rates.

Website addresses should be linked and should point to active sites when available.

With a strong LinkedIn profile and active site engagement, recruiters are more likely to find you.

We are just curious about your site that's been always in the top 10 of active sites on CommentLuv.

These nanowires have a high surface area — to - volume ratio, which enhances the number of active sites for catalytic reactions.

These studies would seem to suggest, therefore, the unlikelihood of the emergence of completely new active sites in non-catalytic scaffolds.

Indeed, Ago - mRNA footprints were rich in miRNA binding sites, suggesting that this approach may predict active sites with far better specificity than other methods.

These tagged glucose cells accumulate in the cancerous tissue and can be seen as active sites of cancer growth.

We provide experimental and computational evidence that conformational flexibility can assist the emergence and subsequent evolution of new active sites by improving substrate and transition - state binding, through the sampling of many potentially productive conformations.

To increase screening success, Zhou chose a probe that specifically binds to the Pin1 enzyme active site very tightly, an approach that is not commonly used for this kind of screen.

In their effort to «stretch palladium as far as it would go,» Delferro and Lipshutz spread the palladium on the iron nanoparticles in a way that maximized the number of active sites where the palladium atoms could interact with nitro - aryl groups.

Many researchers investigate how hydrogen and oxygen come together and chemically react on regions of the catalyst's surface called active sites.

The best - known and most active site for crowdfunding projects, Kickstarter, says it is not interested in the equity market.

Enzymatic activity, assayed with an RNA substrate that is complementary to the catalytic RNA active site, coincides with the cooperative structural transition.

The ribozyme active site also makes tertiary contacts with a tripod of 2» - hydroxyls on the minor groove surface of the splice site helix.

«The developed zeolite is one of the few examples of a catalyst with well - defined active sites evenly distributed in the zeolite framework — a truly single - site heterogeneous catalyst,» says Professor Johannes Lercher.

The generation of completely new active sites capable of enzyme catalysis is, arguably, one of the most fundamental unsolved problems in molecular biology.

We have previously used this approach to demonstrate phenotypic robustness for the antibiotic degradation activity at the natural active site of the GNCA β - lactamase11.

While many contemporary artists exploit the tension between logos and form (consider Tauba Auerbach's Alphabet motifs) or try to press the gray area between design and abstraction into some kind of socially active site (Liam Gillick ’s

Some of the best and most - studied molecular catalysts for H2 activation contain an enzyme - inspired active site.

Using sophisticated microscopy at Oak Ridge National Laboratory (ORNL), researchers were able to directly observe the single - atom active sites in the novel material where catalysis takes place, which provided unique insights into the PGM - free material's efficiency potential.

Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites.

But what is the mechanism for how the nitrogenase active site iron - hydrides relaxed to make this H2?

ROXY1 / 2 belong to a land plant - specific class of GRXs comprising 21 members with a CC - type active site motif, deviating from the ubiquitously occurring CPYC and CGFS GRX classes.

The Pin1 - ATRA complex structure suggests that ATRA is trapped in the Pin1 active site by mimicking an unreleasable enzyme substrate.

The study also found that positive selection more often act on residues adjacent to, rather than directly at, a critical active site of the enzyme, and on flexible regions rather than on rigid structural elements of the protein.

Fracking fields around the town of Blackpool have recently been boosted by investment potentially amounting to # 160 million, and consent is being sought to set up seven new fracking test sites in north - west England, in addition to an already active site at Elswick.

Three positive, conserved electrostatic patches on the N - terminal domain of DnaB may also serve as a binding site for DNA and thereby guide the DNA to a DnaG active site.

A single - stranded, 3» extension of three nucleotides bound to the 3» to 5» exonuclease active site.

«Breaking down metal oxide into tiny particles increases its surface area and exposes lots of ultra-small, interconnected grain boundaries that become active sites for the water - splitting catalytic reaction,» Cui said.

Klenow fragment of Escherichia coli DNA polymerase I, which was cocrystallized with duplex DNA, positioned 11 base pairs of DNA in a groove that lies at right angles to the cleft that contains the polymerase active site and is adjacent to the 3» to 5» exonuclease domain.

To test that hypothesis, the researchers mutated the PETase active site to make it more like a cutinase.

With help from the computational modeling scientists at the University of South Florida and the University of Campinas in Brazil, the team discovered that PETase looks very similar to a cutinase, but it has some unusual features including a more open active site, able to accommodate human - made rather than natural polymers.

They react with light to harden into the three - dimensional structure, and still retain active sites for chemical reactions to occur,» said Sebastián Manzano, a graduate student in the Department of Chemistry at Iowa State and who conducted most of the experiments.

The researchers found that 5 percent of babies born to moms living within a kilometer of not - yet active sites were underweight, whereas 7 percent of births that happened after sites became active were underweight.

In the early 2000s, Maria's group had pioneered the single - atom approach for metals anchored on oxide supports as the exclusive active sites for the water - gas shift reaction to upgrade hydrogen streams for fuel cell use.

By comparing high - resolution structures of two complexes — one containing both a DUB and a pseudo-DUB, and two copies of an inactive DUB by itself — the team determined that KIAA0157 alters the shape of the BRCC36 active site, by swinging an amino acid into position to make the complex able to catalyze chemical reactions.

The boron and nitrogen collectively add more catalytically active sites to the material than either element would add alone.

Moreover, the binding with the MMP active site is discussed in the research paper, «Phosphonate Emerging Zinc Binding Group in Matrix Metalloproteinase Inhibitors», published in Current Drug Targets.

One unique characteristic of ATAs is that they recognize two different substrates in the same active site, and it was found that the active - site residue arginine (Arg138) functions on both substrates.

Answering these questions required modeling the many diverse active sites on these polycrystalline bimetallic samples.

Active site cysteine - null glyceraldehyde -3-phosphate dehydrogenase (GAPDH) rescues nitric oxide - induced cell death.

S. Shekhtman, A. Goguet, R. Burch, C. Hardacre, N. Maguire, CO multipulse TAP studies of 2 % Pt / CeO2 catalysts: Influence of catalyst pretreatment and temperature on the number of active sites observed, Journal of Catalysis 253 (2008) 303 - 311.