Sentences with phrase «cell polarity»
When we talk about "cell polarity," we mean that cells have differences or divisions within them that allow them to function properly. This helps them carry out specific tasks or functions within the body. Imagine it like different parts or sections of a cell having their own roles and responsibilities to make it work effectively. Full definition
• Hippocampal Place Cell Activity in Huntington's Disease Transgenic Mice The Journal of Neuroscience • Centennial Celebration of Automation Role of Planar Cell Polarity Signaling in the Control of Learning and Memory
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Alexandra Kumichel (Knust, MPG)-- «Epithelial cell polarity in the embryonic hindgut of Drosophila melanogaster» (2013)
So she took a postdoc at the Institut Jacques Monod in Paris, where she began to study the influence of mechanical forces on cell polarity using optical techniques.
In the broadest sense, this variation in shapes is known as cell polarity, and it is an essential property for a variety of cell functions.
His recent studies are focused on how these small GTPases may regulate cell polarity and the initiation of gastrointestinal cancers.
Andreas Sagner (Eaton, MPG)-- «Evolution of Planar Cell Polarity during wing development in Drosophila melanogaster» (2012)
A research group lead by University of Tsukuba Faculty of Life and Environmental Sciences International Tenure Track Assistant Professor Norio Takeshita (who holds a concurrent post as Group Leader of the Karlsruhe Institute of Technology Department of Applied Microbiology) has succeeded in using a super-resolution microscope to visualize the mechanism by which cell polarity is maintained.
«Super-resolution microscope allows visualization of the mechanism that maintains cell polarity: The key is to repeatedly establish temporary polarity.»
The Hyman lab has a long and distinguished history studying cell polarity, spindle assembly and positioning, and microtubule dynamics.
Anne - Kathrin Classen (Eaton, MPG)-- «Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway» (2006)
Stem cell polarity is established by the PAR complex, comprised of PAR3 / PAR6 / aPKC, to regulate self - renewal and expansion.
The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts.
Together with our foreign partner, Ralph Hückelhoven (Technical University of Munich), we also hypothesize that compatible fungal pathogens use the plant cell polarity machinery to enter into plant cells.
Work in our group is aimed to understand the cellular, molecular and genetic mechanisms that control the establishment and maintenance of epithelial cell polarity.
The new tool emerged from the PhD project of Yara Sánchez - Corrales from the Grieneisen Lab on cell polarity: the ability of cells to distribute internal proteins in order to facilitate communication, movement or growth.
In Drosophila epithelia, the tumor suppressors Fat (Ft) and Dachsous (Ds) regulate cell proliferation, tissue morphogenesis, planar cell polarity and junction tension.
LKB1 acts as a key regulator of cell polarity as well as energy metabolism partly through the activation of the AMP - activated protein kinase (AMPK), a sensor that adapts energy supply to the nutrient demands of cells facing situations of metabolic stress.
The Cell Polarity Signaling one at Bentley University.
In a specific example of this scenario, co-occurrence of two alternative variants of the cell polarity factor Cdc42 in the same neuron was essential for proper development of a single axon and several functional dendrites.
In fact, there's reason to believe that all of the properties of cell biology that made complex life possible in the next geologic era were put in place here: cytoskeletons that allow eukaryotic cells to change shape, and cell polarity that allows cells to send a molecular message to one side of the cell but not the other, and to interact with nearby cells.
The researchers expect regulation of cell polarity to be key to the development of many other human cell types, for example nerve cells.
The coordinated assembly and disassembly of actin in the cell cortex, which lies just beneath the plasma membrane, generates cortical actin waves that are crucial for important cell functions including migration and cell polarity.
These changes are so fundamental that they lead to prominent alterations in cell shape and loss of cell polarity, alterations that ultimately affect the epithelial barrier,» explained d'Azzo.
«Although polarization and asymmetric cell division of zygotes to form the body axis is a common phenomena found in algae, mosses, and flowering plants, the origin of cell polarity and how asymmetric cell division occurs have remained a mystery up to now,» says Dr. Minako Ueda, a lecturer at ITbM, Nagoya University and a leader of this research.
Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops.
Jennifer Fish (Huttner, MPG)-- «The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle - like microcephaly associated (Aspm) protein and epithelial cell polarity» (2007)
Nadine Muschalik (Knust, MPG)-- «Epithelial cell polarity and photoreceptor morphogenesis in Drosophila» (2010)
Tobias Heckel (Hoflack, TUD)-- «Revealing Src tyrosine kinase - dependent signaling pathways in osteoclasts: Implications on actin organization and cell polarity» (2008)
This small set of dynamic protein polymer systems underpins the establishment and remodelling of long range cellular order, cell polarity, shape and division, and plays a critical role in control of the dynamic organisation of the internal membrane - bound compartments that distinguish eukaryotes from their prokaryotic ancestors.
To determine if Lkb1 exerts a coordinated regulation of energy metabolism and cell polarity, we deleted the Lkb1 gene in polarized cells and explored the metabolic consequences.
Cell polarity is fundamental to the development of multi-cellular organisms, playing a central role in proliferation, cell fate diversification and tissue homeostasis or morphogenesis.
The team «Systems Biology of Cell Polarity and Cell Division (CNRS, IPGG, Institut Curie)», manages by Matthieu Piel, CNRS research director, published in Science about ESCRT III and its role when...
Carcinomas arise from epithelial cells, and tumor progression involves a loss of polarity, so an understanding of cell polarity is important in the identification of novel therapeutic approaches to cancer.
Cell polarity is usually lost early during tumor progression, and several polarity proteins have been identified as tumor suppressors.
We combine biochemical, structural, cellular and functional information using purified proteins, mutant and transgenic plants, yeast and chemical genomic screening systems, transient gene expression assays, confocal microscopy and in silico data analysis to compare ROP - centered kinase signaling during cell polarity (in vitro pollen tubes), morphogenesis (whole plant) and pathogenesis (fungi - infected cells).