Such differences could impact the therapeutic utility of the lines and could have implications
in disease development.
«Suppose you have 100 samples from cancer patients that you want to examine to identify genes important
for disease development,» he said.
There is a growing interest in finding alternative therapies, such as a vaccine that could
prevent disease development in genetically susceptible individuals.
Changes in your lifestyle which include proper diet and increased physical activity will increase the body's usage of the visceral fat deposits and decrease the risk for
heart disease development.
Our blood analysis service is widely used in research to advance the molecular understanding of
chronic disease development and improve prediction of disease onset.
There are differences
in disease development and prevalence, differences in stress and exposure to danger in the workforce, and a number of other possible causes of the gender gap in longevity.
This increase in risk is totally independent of any other factors that influence coronary
heart disease development, which makes it a very significant risk factor in and of itself.
The researchers conclude in their paper: «Ultimately, knowledge of the mechanisms by which thirdhand smoke exposure increases the chance
of disease development in exposed individuals should lead to new strategies for prevention.»
Research Focus: Peipei's current research interest focuses on the hematopoietic stem & progenitor cell (HSPC) development towards myeloid lineage and the mechanism of aberrant myelopoiesis
with disease development including cancer and atherosclerosis.
We are giving people the means to battle and potentially
avoid disease development and progression, including those who have a family history of diseases or are cancer survivors and are at higher risk of future bouts with the disease.
While researching the molecular causes of heart failure and new ways to treat it, a Charité - based working group, led by Prof. Dr. Ulrich Kintscher, found that changes in adipose (fat) tissue lipid metabolism
affect disease development.
RESULTS: Hand dishwashing was associated with a reduced risk of
allergic disease development (multivariate analysis, odds ratio 0.57; 95 % confidence interval: 0.37 — 0.85).
By identifying and profiling molecules that differ between different forms of dengue, the researchers lay the foundations for finding biomarkers present at early - stage dengue that are able to
predict disease development.
In these patients, pinpointing the genetic mutations that
drive disease development allows dermatologists to identify people who should be part of melanoma surveillance programs.
«In that way, we followed changes in the pleura
throughout disease development, observing stages of chronic inflammation, activation of pro-oncogenic signaling pathways, and eventually inactivation and / or loss of genes that are the gatekeepers of cancer development,» MacFarlane says.
«Our findings will promote more investigations into how the body and mind are connected
during disease development, and will facilitate better cancer treatments.»
«These results suggest that an early dysfunction of motor neurons in the brain may be a significant contributor to
later disease development and progression, opening the possibility that experimental therapies targeting this «upstream» dysfunction could have a beneficial impact on the disease's catastrophic «downstream» effects,» said Svendsen, the article's senior author.
Data indicate that increased NCF1 protects against SLE while decreased NCF1 raises SLE risk and highlight the pathogenic role of reduced reactive oxygen species in
autoimmune disease development.
Using animal models of precancerous polyps in the bowel, Chung and his team determined that certain types of immune cells within a chronically inflamed intestine can become rewired, causing them — paradoxically — to contribute to
disease development rather than protect against it.
Popko and others are testing an approach to
stop disease development: preserve oligodendrocytes» ability to handle stress.
The results of the study demonstrate that this approach
impedes disease development and increases the lifespan of mice with the mitochondrial defect.
Researchers found that youth with two copies of HLA - DR3 - DQ2 had the highest likelihood of
disease development by age 5.
Our long - term goal is to characterize oral health and disease at the molecular level; in other words, define taxonomic or functional signatures in the supragingival biofilm that represent the ECC - associated oral dysbiosis prior to
clinical disease development,» he added.
Such changes could be due to
gastric disease development or the consequence of long - term use of acid - suppressing drugs that cause changes to the stomach pH - levels, i.e. changes that contribute to more rapid adaptation by mutations of H. pylori.
Access to these new tools allows academic researchers to tackle common diseases, dissecting the complex interplay of genetic and environmental factors that
govern disease development.
Because the liver receives 70 % of its blood supply from the intestine, it is important to understand how the gut contributes to
liver disease development,» explained lead investigator Yu - Jui Yvonne Wan, PhD, Professor and Vice Chair of the Department of Pathology and Laboratory Medicine at UC Davis Health.
5 % mitochondrial carryover is considered a relatively stringent level below
which disease development or transmission are low.
We will review recent data showing how fiber differences between GB diets and purified diets can significantly influence gut health and microbiota, which itself can affect
metabolic disease development.
However, in the past, research into mechanisms of ageing has commonly been researched and treated separately
from disease development.
As a result, they contain a complete set of the genes that resulted in that disease — representing the potential of an almost perfect disease model for
studying disease development, new drugs and treatments.
Dr. Shusheng Wang's team proposes that tiny pieces of genetic material called microRNAs could have a big role in
AMD disease development and therapeutics.
An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development
Aging reduces the ability to benefit from sun stimulation through the eyes, mostly due to eye -
related disease development, especially problems such as glaucoma, and cataracts.
When this is damaged or depressed it causes a weakened anti-oxidant response which results in further genetic damage and
further disease development (10).
Here is the predictable part: ``... the immunological basis of such reactions is unclear, and it is possible that such apparent associations with vaccination may be due to
coincident disease development, particularly in young animals».
Sure, they are selling their service but canine tooth cleaning is what they do and the site states in part «Improper or Incomplete Dental Treatment can lead to... new infections or the spread of existing infections or accelerated tooth decay or
gum disease development.»
Fighting Alzheimer's, Parkinson's, and an Unhealthy Environment The report advocates a series of both personal and societal changes that could make the environment better fit for decreasing the risk of
cognitive disease development.
However, Dr. Hagan emphasized that there is a clear need for further study into the impact of alcohol consumption and other factors
on disease development in PWID, as there are few studies that consistently report this information.
«The ability to identify, characterize and validate gene targets that strongly associate or correlate
with disease development or metastasis will facilitate early detection and appropriate treatments to tackle the disease at an early stage or before metastasis occurs.»
For these reasons, the HD community is in search of good biomarkers, tests that can be easily measured to
predict disease development and response to treatment.