Sentences with phrase «disease recurrence»

Funding of clinical research, disease and health related projects and research related to the understanding of the etiology and treatment of diseases Recurrence of the programme: yearly

The risk of disease recurrence in a five - year time period also must be greater than or equal to 30 percent.

Now researchers from The University of Manchester and University Hospital of South Manchester NHS Foundation Trust — both part of the Manchester Cancer Research Centre — have investigated the role of a molecule known as FAK in controlling the resistance of DCIS to radiation and in predicting disease recurrence.

TBNET proposed new definitions for «cure» and «failure» of MDR - TB treatment based on the sputum culture status at six months after the initiation of therapy, and whether patients were free from disease recurrence one year after the end of therapy.

In melanoma, they can be used to determine tumor stage, diagnosis, therapy selection and when to monitor for disease recurrence.

These patients had an extended period without disease recurrence and longer overall survival.

Ovarian cancer initially recurred in the pelvis of 25 percent of patients while nearly 11 percent had disease recurrence outside of the pelvis.

These studies will investigate whether Src kinase inhibitors are best used in the adjuvant setting post-surgery or after chemotherapy to prevent the formation of local and distant disease recurrence.

The main reasons for this seemed to be less disease recurrence and fewer infusion reactions in the group that underwent proactive trough concentration monitoring.

(In clinical trials, HER2 - positive patients receiving Herceptin and standard combination chemotherapy had a 52 percent decrease in disease recurrence compared with patients treated with chemotherapy alone.)

Toxicity and disease recurrence assessment was conducted weekly while patients received radiation therapy; four months after treatment completion; every three months for one - and - a-half years; every four months between one - and - a-half and three years; every six months in years three to five; and then annually until death.

However, disease recurrence occurs in approximately 50 % of cases.

Natera, a leader in non-invasive genetic testing and the analysis of circulating cell - free DNA, has presented data that validates the ability of Signatera ™ to monitor treatment response, detect minimal residual disease, and identify disease recurrence in bladder and co...

Measuring these residual leukemic cells can be a powerful tool for measuring treatment response, guiding treatment decisions, monitoring remission status, and detecting disease recurrence.

Using advanced high - throughput technology, the laboratory has developed gene signature profiles to help predict disease recurrence and response to medical therapies.

These results appear to translate into better control of disease in the pancreatic region and a longer freedom from disease recurrence.

However, reduced radiation was also associated with a slightly increased risk of disease recurrence.

There were no clinical signs of disease recurrence in these calcium oxalate stone - forming dogs during 12 months feeding of the diet (Stevenson et al. 2004).

Scientists use cancer biomarkers to predict a patient's risk of developing cancer, their prognosis and response to therapy and their chance of disease recurrence.

In patients with acute myeloid leukemia, cancer cells resist the effects of chemotherapy, many times resulting in disease recurrence and ultimately death.

Professor Nigel Bundred, from The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, who led the study, said: «We know that different subtypes of invasive breast cancer have different levels of disease recurrence.

A recent study by researchers from the Manchester Cancer Research Centre, published in the journal Annals of Oncology, has explored potential subtypes of DCIS and whether these subtypes relate to disease recurrence.

Results of an EORTC trial appearing in The Lancet Oncology show that adjuvant Ipilimumab significantly improves recurrence - free survival in patients with completely resected stage III melanoma at high risk of disease recurrence, but that this treatment was also associated with a high rate of immune - related adverse events.

«Patient age, cardiac risk, and disease recurrence risk should be considered when selecting candidates for hormone therapy in this patient population,» said Nataniel Lester - Coll, MD, first author on the study and a Resident in the Department of Therapeutic Radiology at Yale School of Medicine.

Ultimately, for this patient population, the findings translate to approximately 90 percent chance of local disease control at 1 year, and > 20 months free of any disease recurrence.

Some side effects can be so debilitating that patients decide to quit therapy and risk disease recurrence or progression.

Many ovarian - cancer patients in Dr. Odunsi's CRI / Ludwig CVC Trials Network clinical trials show encouraging results, including significant delays in time to disease recurrence and, in some cases, remission.

That meant the risk of disease recurrence and new cancer was 34 percent lower among women who continued the aromatase inhibitor for 10 years compared with the other group, researchers said.

That means they have a high likelihood of disease recurrence and poor survival odds despite receiving standard chemotherapy and optimum surgery.