The word
"endogenous" refers to something that originates or comes from within a particular system or organism.
Full definition
Recently, prospects for xenotransplantation brightened when Harvard geneticist George Church demonstrated the removal of dozens of
endogenous retroviruses from the pig genome, in a tour de force of the CRISPR / Cas9 gene editing technique.
Molecular hydrogen appears to stimulate the production of
endogenous antioxidants via the Nrf2 Pathway, meaning it up - regulates the body's own antioxidant system.
No matter what glucose the human brain would need for whatever purpose, it's going to have it because of
endogenous production in the liver.
His pioneering mouse embryonic stem (ES) cell work in the 1980s, demonstrating germ - line transmission and the great potential of ES cells to generate mice carrying mutations
in endogenous genes, established milestones in a field that saw the award of the 2007 Nobel Prize in Physiology or Medicine to Mario Capecchi, Martin Evans, and Oliver Smithies.
Amabile A, Migliara A, Capasso P, Biffi M, Naldini L, Lombardo A. Inheritable silencing of
endogenous genes by hit - and - run targeted epigenetic editing.
Natural Bio-identical hormones are identical, on a molecular level, with
endogenous hormones in hormone replacement therapy.
The first is prevention
with endogenous antioxidants — superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase work together to stabilize then break down the free radical so it can be used to regenerate glutathione, the body's most potent antioxidant.
Retinal regeneration by de-novo neurogenesis, a damage induced process
by endogenous cell sources, is well established in retina of some species, like fish and chick, but does not occur spontaneously in mice and humans.
These receptors allow cell to cell communication — they are like a lock with the neurotransmitter or chemical, such as
endogenous opioids called endorphins, acting like a key.
Chia - Shan Wu, Christopher P. Jew, Hui - Chen Lu (2011) «Lasting impacts of prenatal cannabis exposure and the role of
endogenous cannabinoids in the developing brain», Future Neurology, 6:459 - 480.
For more information on other CRISPR / Cas systems used
for endogenous protein tagging, please visit our website
This study represents the only research done so far
on endogenous retroviruses of New World bats and suggests there is still much to be learned about vampire bats as viral reservoirs.
lab has developed a CRISPR / Cas - based system for tagging
endogenous proteins with an auxin - inducible degron (AID) tag to generate proteins which can be
The results of this large - scale prospective study revealed that high
endogenous levels of testosterone are associated with low mortality from all causes.
«Report on the National Eye Institute Audacious Goals Initiative: Replacement of Retinal Ganglion Cells from
Endogenous Cell Sources,» by Monica Vetter and Peter Hitchcock, Translational Vision Science & Technology, March 2017.
According to one study, milk thistle protected the heart
from endogenous antioxidant enzymes, and protected the heart from a further drop in blood pressure.
Aghion and Howitt are well known for their work in the subfield of macroeconomics known
as endogenous growth theory.
HGH Spray Plus contains human growth hormone boosters and vital amino acids to provide a safe, effective, and legal boost in
endogenous growth hormone levels *.
The virus, called
human endogenous retrovirus W (HERV - W), codes for a protein that, when activated, sets off an inflammatory cascade in the brain that leads to symptoms.
It is «remarkable» that the amphora «should release
endogenous DNA by simply swabbing the surface,» Oliver Craig of the University of York in the United Kingdom said via e-mail.
Clomid certainly can
increase endogenous testosterone production while still boosting fertility.
To characterize the dose - response relationship between
endogenous sex hormones and bone sarcoma risk, a study providing information on lifetime gonadal hormone exposure would be required.
«Therefore, the decrease in
endogenous estrogen during perimenopause may be linked both to a decrease in sexual function and to an increase in cardiovascular risk.»
Using a small amount of a radioactive substance as a tracer, the scientists focused on the brain's mu - opioid system in which chemicals
called endogenous opioids bind to receptors and hinder the spread of pain messages in the brain.
We are seeing, for the first time, that these nanoparticles can markedly reduce IOP by reducing
endogenous expression of TGF - β2.
Subsequently, he established carbon monoxide as another gaseous transmitter and D - serine as a glial derived
endogenous ligand of glutamate - NMDA receptors.
• Fewer than normal lymphocytes Lymphopenia (decreased numbers) commonly occurs with excess glucocorticoids, whether they be from
endogenous sources (stress, debilitating disease, surgery, shock, trauma, or exposure to heat or cold), or from exogenous sources (such as glucocorticoid therapy).
Efforts to
tag endogenous genes for proteins in these compartments using CRISPR systems should strongly consider using moxFPs over standard FPs for the reasons listed above.
Mai said that «in the future, we plan to combine our tool with genome editing, which we will use to specifically insert sequence encoding CIB1 into the genome, enabling us to optogenetically control the intracellular membrane
using endogenous proteins.
Targeted nutrients including choline, arginine, ornithine, glycine, glutamine, and niacin (vitamin B3) can help
support endogenous GH secretion, assist muscle growth and recovery from exercise, and promote healthy sleep.
In 1995 he and his colleagues discovered the first
endogenous inhibitors of HIV, namely some of the beta chemokines.
Removing the viruses — called
porcine endogenous retroviruses, or PERVs — creates piglets that can't pass the viruses on to transplant recipients, geneticist Luhan Yang and colleagues report online August 10 in Science.
And additional research has uncovered gender differences: women appear to have more kappa opiate receptors, which also bind with
endogenous pain killers.
In addition, the researchers showed that Cbf - beta maintains the osteoblast lineage commitment in two ways — through the Wnt paracrine pathway to affect nearby cells and through
endogenous signaling within the cell to suppress adipogenesis gene expression.
His research focus is on the mechanisms by
which endogenous cellular proteins impact retroviral replication, in particular the interaction of cellular TRIM5α with retroviruses such as HIV - 1.
A human RNU48 and actin TaqMan probes were used as
endogenous controls for miRNA and regular gene expressions, respectively.
Two
known endogenous skin antioxidants are present in goji berries, heme oxygenase - 1 and metallothionein, which were found to be involved in the photo immune protection.
Your body's supply of
endogenous digestive enzymes like trypsin and chymotrypsin are one of your first lines of defense against developing cancers in the body.
The main difference
between endogenous cannabinoids and opioids, Felder explains, is that cannabinoids are part of the fat family, which also distinguishes them from other neurotransmitters.
You'll burn off most of that glycogen before dipping
into endogenous fat stores.
It instead relies on treatments such as chemotherapy or local radiation to lyse tumors and release
endogenous antigens, which are then captured by neighboring G100 - activated dendritic cells, and is intended to generate a broad and varied immune response.
Phrases with «endogenous»