Sentences with phrase «function of genes»

There was zero discussion of the known functions of these genes in this paper, so it's difficult to say.
The variant has been found in two men with prostate cancer, and in vitro analysis suggests it causes a partial loss of function of the gene.
But such similarities are inherently intellectually sterile, unless the biological functions of the genes have been established for one or more of the species being compared.
We study learning and memory at the genetic level to understand the structure, regulation, evolution and biological function of genes that are required for normal learning and memory.
Genetics (GEN): The study of molecular genetics focusing on the structure and function of genes at a molecular level.genes, genetic variation, and heredity in living cells.
Korenberg was the early pioneer of studying these individuals with partial gene deletions as a way of gathering clues to the specific function of those genes and gene networks.
«Fruit flies reveal normal function of gene mutated in spinocerebellar ataxia type 7.»
Furthermore, despite the claim that evolution has no application, phylogenetic comparisons of humans and other organisms allows us to identify the precise location and putative function of genes responsible for developmental disorders.
Published in GigaScience, the open source Galaxy workflow allows researchers to make easier work of finding gene families; an important tool when it comes to analysing the evolution, structure and function of genes across species.
«If you line up these [variants] and determine the likely function of the genes, do they tell the same story?»
Researchers at VCU Massey Cancer Center have uncovered a novel function of the gene PLK1 (polo - like kinase 1) that helps prostate cancer cells metastasize (spread) to other parts of the body.
The precise function of these genes is unknown, but previous research suggests they may be involved in removing a protein fragment called beta - amyloid from the brain.
«Solving a genetic mystery in type 1 diabetes: Research unveils function of gene associated with higher risk of autoimmune attack.»
Students use online databases - including WormBase and Pubmed - to explore the molecular genetics and physiological functions of the genes targeted by RNAi.
Also relevant are studies of the upstream mechanisms that regulate levels and function of those gene products, for example: how a transcription factor regulates multiple targets or how factors can regulate translation or post-translational modification of multiple proteins.
In the case of CHD2, scientists collaborating with the EuroEPINOMICS RES consortium used antisense technology to rapidly generate zebrafish larvae with a partial loss of function of this gene, and were then able to detect epileptic seizures in these animals using electrographic analysis (this method is very similar to electroencephalography, or EEG, which is used to analyze seizures in humans).
Over the longer term, the identification of the coffee tree genome sequence opens up new possibilities for varietal improvement, knowledge of the specific functions of the genes (in particular those specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools for the function of the plant.
This shuttling mechanism is crucial to maintain normal function of our genes and prevent disease.
Essentially the model reproduces the inner workings of all of the proteins within the organism and allows scientists to see everything from how cells interact with each other to the functions of genes in a larger context that had not been previously understood.
Genetic modification is a useful tool to help understand the function of genes.
Genetic modification is a useful tool to help us understand the function of genes.
The answers could help open many doors in medicine and greatly expand our understanding of the functions of genes.
Carlo Croce, a cancer researcher at Ohio State University in Columbus, and his colleagues created a diagram of interacting miRNAs for normal body cells by connecting them according to which genes they target and the function of those genes, in a way similar to analyses of human social networks.
The function of the EST — or at least the function of the genes from which they are derived — is therefore known.
Although the function of the gene isn't fully established, it is thought to add sugars to proteins, which could alter the speed or specificity of their usual function.
With rapid advances over the past 10 years in technologies for discovering and analyzing the functions of genes, researchers are now increasingly able to get at the biological roots of complex disorders such as substance abuse and addiction.
... What we learn improves our knowledge about the function of these genes in other animals, including humans.»
While earning a master's degree in biology at the University of Vienna in his native Austria, he spent more than a year researching the function of genes in bone development and cancer in Erwin Wagner's lab, which was located at the Research Institute of Molecular Pathology (IMP) in Vienna.
Understanding the function of this gene — described this month in journal Molecular Psychiatry — could lead to more effective treatments for schizophrenia.
All this enabled them to systematically whittle away genes that either had nonessential functions or duplicated the function of another gene.
However, resistance to therapy might go beyond cancer mutations that usually alter the function of genes.
Discovering the function of a gene requires cloning a DNA sequence and expressing it.
These adducts may also change the functions of genes that promote or suppress disease, although exactly how they might lead to developmental decrements in fetuses exposed to them is unclear.
Researchers at the ARC Centre of Excellence in Plant Energy Biology at the University of Adelaide's Waite campus then investigated the function of this gene.
Dr Yalda Jamshidi, Senior Lecturer in Human Genetics, St George's University Hospital Foundation Trust, said: «Inherited genetic conditions often result because the function of a gene is disrupted.
In the next phase of the study, we will examine and categorize the functions of the genes that we identified — not only in model organisms, but also in agriculturally and economically important crops such as corn.»
IMPC builds on the groundwork and achievements of EUMODIC in establishing the procedures and processes to identify and catalogue the function of genes.
«Certainly, a lot of details are still unclear especially with regard to the function of genes.
Although the functions of these genes match well with the environment in which woolly mammoths were known to live, Lynch warns that it is not direct proof of their effects in live mammoths.
«To have an idea of what these genes might do, I searched a database that describes the functions of genes in the mouse and found that mice that have a deletion of the Maged1 gene have neurocognitive behavioral abnormalities.
The difficulties are well illustrated by last month's rejection of a patent application in the US, by the Institutes of Health, for DNA sequences without knowledge of the function of the gene.
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