Sentences with phrase «target site»

The update is suspected of targeting sites emphasizing revenue over quality content.

Fully understanding this process may present new target sites for drugs and may lead to better treatments for neurological diseases, cancers and other disorders.

You'd then want to target sites where these people hang out.

One of the keys to success — and best ways to scale — is to not just target sites based on their content.

A highly targeted site is designed for a specific niche market, such as first - time buyers, seniors, or owners of high - end properties.

In many diseases, however — for example of the central nervous system — it is of decisive importance to transport the active substance as efficiently as possible to the required target site.

Sharing this information in your dating profile or on the right targeted sites can help you to get what you want sooner.

If targeting both sites, keep the audience in mind when choosing photos to add to boards.

So, let's say you've come up with a nice mix of target sites.

In some cases the reduction in protein expression could be reversed by deletion of predicted microRNA target sites in the variably included region.

Doudna and her research group have focused on the Type II system which relies exclusively upon RNA - programmed Cas9 to cleave double - stranded DNA at target sites.

Scammers typically target sites with free signups.

It has even organised mass email campaigns asking major corporations to pull adverts from targeted sites.

The results could help improve scientists» ability to build molecules that interlock very specifically with target sites on proteins — a fundamental part of designing new anti-cancer drugs.

The miR -142-3p target site within the pCMV - Neo-APC plasmid sequence was mutated to produce the pCMV - APC mutant plasmid (Figure 3B).

«So, with this knowledge, the dream is that we could eventually use gene editing technology to edit the microRNA target sites in the host plants, preventing the microRNAs from binding and silencing these genes.

Simply install the pixel and you can now target your sites visitors on Twitter.

Instead of being diluted in the blood, drugs put in the vesicles would reach target sites in concentrated doses

To determine whether the growth advantage conferred by X4 - ZFNs treatment in the presence of X4 - and R5X4 - HIV resulted from a survival advantage of CXCR4 disrupted cells, we performed flow cytometry at various time points post infection as well as deep sequencing of the X4 - ZFNs target site on HIV - infected and uninfected cultures.

In addition to the obvious advantages SapTrap offers for tagging a single genetic locus, the toolkit also offers repair templates for tagging proteins in a tissue specific manner, as well as 3 - site destination vectors for inserting a tag at multiple target sites.

Graphical representation of indels created at the CD81 target site in different CRISPR / Cas9 - edited hiPS cell clones.

Sequencing - amplifying target site and sending for sequencing will identify those clones that have one or more alleles that have been modified

Goldcrest typically targets sites where perceived problems exist — such as planning, conveyance, contamination, technical challenges, railway tunnels, squatters — all of which drives the initial purchase price down and keeps competition at bay.

The hackers that targeted the site took a recently rebranded currency called Nano (formerly Raiblocks).

Refers to a set of SEO tactics that attempt to increase the rankings of target sites through manipulation such as cloaking, keyword stuffing and robot - driven link building.

Sophisticated users target a site by bombarding it with thousands of «zombie» machines, called...

Passive targeting nanomedicines are not enough to improve the drug accumulation at the tumor target site for the high hypovascularization level.

It's certainly rather ironic now Ashley Madison is in the grips of one of the industry's biggest security breaches — with hackers specifically targeting the site with a prolonged and zealous campaign to try and bring the site down.

(B) Schematic representation of the pCMV - Neo-APC expression vector that codes the full - length APC sequence together with wild - type or mutated miR - 142 targeted site located at the 3 ′ UTR.

After target site - based (kdr) pyrethroid resistance was detected in 2004 and rose in frequency the carbamate bendiocarb was introduced for IRS.

Tomahawks that Pentagon officials also said targeted the site.

This data gives you a sense of how targeted a site is, and how much impact it will have beyond SERP impact.

There is no «One Size Fits All» Solution: Staggered start - up schedules, targeted site analysis, and customized delivery models are some of the strategies that helped make implementation a success in Memphis City Schools.

It's been reported (by a number of sources) that the Russian Federation «warned» yesterday, 4/12/18, that if any US missiles target sites in Syria, then the Russian assets would attempt to shut down the missiles and the launching sites would be targetted.

In the fall of 2015, Port of Oswego officials targeted a site in Jamesville for the inland port, rather than the 3Gi site.

Several of those changes corresponded with the viral target sites of two of the cocktail's antibodies, triggering an in - depth molecular analysis of the development and impact of those changes.

Advantageous mutations in the insecticide target site are a major source of resistance, highlighting the direct impact of human interventions on the mosquito genome.

«To reduce off - target effects, we introduced preassembled Cpf1 RNPs into cells, assuming that Cpf1 RNPs, similar to Cas9 RNPs, would cleave target sites immediately after transfection and would be degraded rapidly by endogenous enzymes that break the proteins, thereby reducing off - target effects without sacrificing on - target effects.»

In sum, Cpf1 is expected to broaden the scope of CRISPR genome editing target sites with enhanced efficiency.

Here, we identified the importin - binding region in p38 and JNK and developed a myristoylated peptide targeting this site that we called PERY.

The major finding was that an early and strengthening attachment to the glycans at the V2 target site appeared to be very important.

These mutations can occur at the molecular level, preventing the insecticide from binding to an enzymatic target site.

For the primary landing scenario, targeting Site J, Rosetta will release Philae at 08:35 UTC (12:35 a.m. PST; 9:35 a.m. Central European Time) at a distance of 14 miles (22.5 kilometers) from the center of the comet, landing about seven hours later.

We found that KLF4, which is one of the IPS genes, is among the highest scored genes on the target list and that there are 2 potential miR7 target sites in 3 ′ UTR region of this gene.