Sentences with phrase «tissue homeostasis»
Tissue homeostasis refers to the balance and stability maintained within a tissue or organ in our body. It means that the cells in the tissue are functioning properly and the tissue remains healthy. This balance is crucial for our body to work effectively and stay in good condition. Full definition
For example, hGDAsBMP express higher levels of such astrocyte - related genes as glutamate transporter 1, connexin 43, and AKAP12, which are relevant to maintaining tissue homeostasis in the CNS as well as reducing astrogliosis and neuronal death after injury, mediating glutamate uptake and promoting blood - brain barrier formation [23], [24], [58]--[61].
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Furthermore, CD47 is known to be a key regulator of tissue homeostasis, and is also involved in a variety of diseases ranging from atherosclerosis to cancer.
Peroxynitrates results in lipid peroxidation of membranes and cause disturbances in tissue homeostasis that is severe enough to cause cellular damage and eventually cell death (Beattie et al., 2000).
His current research is directed toward understanding the molecular genetic mechanism by which stem cells regulate tissue homeostasis, regeneration, and tumorigenesis.
Toxicology and compound testing The zebrafish model system is ideal for testing biological effects on tissue homeostasis and organism development of substances and pollutants.
«Importantly, this knowledge will help us better understand healthy tissue homeostasis and the wide range of diseases that involve abnormal tissue mechanics, especially cancer.»
Ultimately, the reeducation of stromal cells to recover the control mechanisms responsible for normal tissue homeostasis might be an innovative strategy to support the current cancer treatments.
We are interested in the mechanisms that support tissue homeostasis and cancer metastasis.
«The circadian clock was not regulating the functions associated with tissue homeostasis but rather functions linked to the specific stress experienced by each kind of tissue,» Francisca explains.
Main interest of the Unit is to unravel the key molecular and cellular mechanisms controlling immune tolerance, responsible for maintaining tissue homeostasis and avoiding adverse immune responses.
They may act as microbial or danger sentinels, fight microbes, or regulate tissue homeostasis.
Our experiments demonstrate that, despite the weight loss, IF treatment induces undesirable effects on tissue homeostasis.
First, senescence depletes the supplemental pool of stem cells or progenitor cells that leads to the continuous decline of tissue homeostasis and accelerates organ aging.
«This study provides new insight into the pathways that regulate immune responses to commensal bacteria and maintain tissue homeostasis» adds Hepworth.
«The worm was initially used as a model to study embryology and neurobiology, and starting in the late 1990s research expanded into stem cell biology, tissue homeostasis, and regeneration, topics that are still very actively studied today,» he says.
Stem Cells and Tissue Homeostasis (Institut Curie / UMR 3215 CNRS / U934 Inserm), managed...
It is currently largely unclear how cells initiate these alternative cell cycles, and what their functional importance is for tissue homeostasis.
Here, we review work that has revealed the central role that physical forces and extracellular matrix mechanics play in the control of cell fate switching, pattern formation, and tissue development in the embryo and how these same mechanical signals contribute to tissue homeostasis and developmental control throughout adult life.
ILC3s function in concert with T cells in maintaining tissue homeostasis and protecting the host during bacterial infection [11].
Cell polarity is fundamental to the development of multi-cellular organisms, playing a central role in proliferation, cell fate diversification and tissue homeostasis or morphogenesis.
The basement membrane (BM) is a dense, tightly cross-linked matrix that acts as physiological barrier to maintain tissue homeostasis.
Chromosomal instability and tissue homeostasis.
The «Meet Our Scientists» video entitled «Our relative the fly» presents the research performed by Marco Millán on the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, tissue homeostasis, and tumorigenesis.
Aberrant regulation of the epigenetic information results in changes in cell fate decisions, thereby affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.
Programmed cell death is essential in organ development and tissue homeostasis and its deregulation is associated with the development of several diseases in mice and humans.