Sentences with phrase «tissue sarcoma»
"Tissue sarcoma" refers to a type of cancer that originates in the body's connective tissues, such as muscles, bones, or fat cells. It is a malignant tumor that can grow and spread to other parts of the body. Full definition
Hemangiosarcoma is a very aggressive, high - grade soft tissue sarcoma with the most common areas affected being the spleen and heart.
caninecancerawareness.org
The research parallels that done for human cancer treatment and is showing good results in shrinking soft tissue sarcomas with few side effects, according to a report from scientists at Heska Corporation2.
If the ongoing trials produce a sufficiently robust clinical benefit for patients, we plan to pursue soft tissue sarcoma as the first indication for which we intend to seek regulatory approval for CMB305.
Research on mouse tumors resembling rhabdomyosarcoma, the most common soft tissue sarcoma in children, revealed that the immune system's T cells may be just as critical to fighting tumor cells as the viral therapy injections themselves.
Shortly after arriving in Washington, Baba was diagnosed with a soft tissue sarcoma by his local veterinarian.
In 1991, veterinarians noticed a huge increase in the incidence of soft tissue sarcomas at the sites of vaccinations (such as on the rear limbs or between the shoulder blades).
From The Roanoke Star When Kitty Smith, of Christiansburg, Virginia, learned her 9 - year - old cocker spaniel, Maddi Lynn Grace, had been diagnosed with a soft tissue sarcoma on her left front leg earlier this year, she knew right away that she would take her beloved companion to the Virginia - Maryland College of Veterinary Medicine at Virginia Tech for treatment.
Dr. Grier is an active member of the Bone Tumor Disease Committee and the Soft Tissue Sarcoma Committee of this group.
The study included 835 soft - tissue sarcoma patients who were treated with surgery with curative intent between 1994 and 2016.
Synovial sarcoma is a rare soft tissue sarcoma characterized by a t (X; 18) translocation, which results in a SYT - SSX gene fusion.
Because there is no established standard - of - care for soft - tissue sarcoma aftercare, Posch and colleagues conducted a study with the hypothesis that «the rate is much more informative than the risk» when it comes to recurrence or metastasis; in other words, though there may be a certain percentage risk of recurrence over 5 years, understanding when those events tend to occur is more useful for patients.
My primary research focus has been in the use of individualized approach in the management of gynecologic cancer, extremity soft tissue sarcoma through molecular markers and precision radiotherapy.
Soft Tissue Sarcoma Opportunity: in both our monotherapy single arm Phase 1 and combination randomized Phase 2 studies, we are focusing on two types of sarcoma where we believe there is significant unmet need: synovial sarcoma and Myxoid round cell liposarcoma.
There have also been reported increased incidence of soft tissue sarcomas occurring at vaccination sites and the Vaccine - Associated Feline Sarcoma Task Force (VAFSTF) was formed in November 1996 in the USA in response to that.
Canine: The Identification of a Metastatic Signature in Canine Soft - Tissue Sarcomas D09CA - 031, Marlene L. Hauck, Grant Amount: $ 141,751
Treatment for soft tissue sarcomas depends on the tumor size and location.
Hemangiosarcoma — very aggressive, high - grade soft tissue sarcoma with the most common areas affected being the spleen and heart.
Cytology can sort out the difference between mast cell tumors and soft tissue sarcoma as well.
Rhabdomyosarcoma is a pediatric malignancy of the muscle that is also the most common soft tissue sarcoma in children.
At the Children's Oncology Group, we work on the design and implementation of studies regarding Ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and other soft tissue sarcomas.
He is a «medical oncologist and hematologist with a special interest in the diagnosis, clinical care, and investigation of patients with malignant mesothelioma and soft tissue sarcoma,» according to an online biography on the school's website.
This pilot research builds on an earlier study by Milovancev and collaborators that examined the ability of MRIs and CT angiograms to detect cancerous lesions related to FISS, and another study that looked at three methods for assessing margins for canine mast cell tumors and soft tissue sarcomas.
The pharmaceutical firm Parke - Davis & Co. made various formulations of Coley's Toxin available to all physicians from 1899 to 1951, and at least 42 physicians from Europe and North America reported success stories in patients treated with the toxin, specifically for bone and soft - tissue sarcomas.
Dioxin is strongly suspected of being a human carcinogen, linked with both soft - tissue sarcomas and non-Hodgkin's lymphomas.
GD2 is found on the surface of almost all neuroblastoma cells as well as other tumors, including the skin cancer melanoma, the bone cancer osteosarcoma and soft - tissue sarcomas.
Specifically, the FACC - 29 includes 29 cell lines of canine origin, including 10 osteosarcomas, 5 melanomas, 2 mammary carcinomas, 1 hemangiosarcoma, 2 bladder carcinomas, 4 lymphoma / leukemias, 1 mast cell tumor, 2 histiocytic sarcomas, 1 thyroid carcinoma and 1 soft - tissue sarcoma.
The antigen, GD2, is also carried on the surface of melanoma, the bone cancer osteosarcoma and some soft - tissue sarcomas.
Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II / III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC # 737754, IND # 118613)
A Phase 1b (Open - Label) / Phase 2 (Randomized, Double - Blinded) Study Evaluating Gemcitabine and Docetaxel With or Without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma
This randomized phase II / III trial studies how well pazopanib hydrochloride, combination chemotherapy, and radiation therapy work and compares it to radiation therapy alone or in combination with pazopanib hydrochloride or combination chemotherapy in treating patients with newly diagnosed non-rhabdomyosarcoma soft tissue sarcomas that can be removed by surgery.
It is not yet known whether radiation therapy works better when given with or without combination chemotherapy and / or pazopanib hydrochloride in treating patients with non-rhabdomyosarcoma soft tissue sarcomas.
An analysis of more than 800 patients found that the one - size - fits - all approach to «aftercare» for localized soft - tissue sarcoma is misguided.
Li - Fraumeni syndrome (LFS) is a genetic disorder associated with an increased risk of developing several forms of cancer, including soft tissue sarcoma, breast cancer, leukemia, lung cancer, brain tumors and adrenal gland tumors.
Two antibody immunotherapies are approved for sarcoma patients, the RANK - targeting denosumab (Xgeva ®) for bone sarcoma (osteosarcoma) and the PDGFR - targeting olaratumab for soft tissue sarcoma.
Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma.
When just the soft - tissue sarcomas were considered, the results were similar, with a clinical benefit rate of 42.5 %.
The most common tumor type was salivary gland tumor (22 %), followed by other soft tissue sarcomas (20 %), infantile fibrosarcoma (13 %), thyroid tumors (9 %), and other malignancies occurring in 4 or fewer patients.
He is a member of the Children's Oncology Group Subcommittee for Soft Tissue Sarcoma and the American Association for Cancer Research.
New insights into those questions could also lead to more effective ways of preventing cancer in the first place, says Dr. Ohm, who has a special interest in rare soft - tissue sarcomas.
With a focus on high - tech radiotherapy such as image guided radiotherapy (IGRT), stereotactic body radiotherapy (SBRT), brachytherapy and radiobiologic modulation of tumor response, I have had the chance to use precise radiotherapy to treat variety of tumor sites such as genitourinary, gynecologic, soft tissue sarcoma, gastrointestinal, head and neck cancer and metastatic disease.
The Sarcoma Program at the Johns Hopkins Kimmel Cancer Center in Baltimore provides comprehensive care for pediatric and adult patients with bone and soft tissue sarcomas.
Treated tumor types include hepatocellular carcinoma, cholangiocarcinoma, neuroendocrine tumor, colorectal cancer, breast cancer, melanoma, and soft tissue sarcoma.
Status: CMB305 is currently in several stages of clinical development, including a monotherapy Phase 1 trial and a fully - enrolled randomized Phase 2 trial, primarilyin patients with two subtypes of soft tissue sarcoma (synovial sarcoma or myxoid / round - cell liposarcoma).
Immune Design entered into a clinical trial collaboration with Genentech, a member of the Roche Group, to evaluate the safety and efficacy of its CMB305 cancer immunotherapy product candidate combined with the investigational cancer immunotherapy atezolizumab in a randomized Phase 2 trial in patients with soft tissue sarcoma.
In 25 soft tissue sarcoma (STS) patients with recurrent disease treated with CMB305, median overall survival (mOS) had still not yet been reached, with an overall survival rate at 12 and 18 months of 83 % and 76 %, respectively.
About CMB305: CMB305 is a prime - boost approach designed to target tumors that express the NY - ESO - 1 tumor antigen, such as soft tissue sarcoma, the lead indication we are studying in Phase 1 and 2 clinical studies.
The multikinase angiogenesis inhibitor pazopanib was well tolerated and exhibited some responses in pediatric patients with soft - tissue sarcomas and other refractory solid tumors in a phase I trial.