The word
"transgenic" refers to something that has been genetically modified by introducing genes from one organism into another organism. It means scientists have altered the genetic makeup of an organism by adding genes from a different species.
Full definition
Both 3DISCO and CLARITY have relied on the use of
transgenic mice in which a subpopulation of neurons are brightly labeled with GFP (e.g. Thy1 - YFP - H mice).
For their investigation, the researchers first developed a disease model
of transgenic mice expressing elevated levels of TDP - 43 to capture the pathology of sporadic ALS / FTD.
(B) GUS induction
in transgenic plants in response to increasing ligand concentration.
We then tested the response of
transgenic plants with the sensing and de-greening gene circuits to the TNT ligand using conditions that mimic real - world situations.
Use of
transgenic animals in the study has been approved by the Biosafety Committee of the Universitat Autònoma de Barcelona.
Biosafety and risk assessment framework for selectable marker genes in
transgenic crop plants: a case of the science not supporting the politics.
Using transgenic mouse models, Ashlyn's work established that an increase in global androgen receptors influences neural sex differences and sexually differentiated behaviors analogous to loss of AR function.
Using diet - controlled experiments and reporter
transgenic lines for critical signalling pathways, our aim is to identify the molecular and cellular apparatus that tightly coordinates growth and differentiation with the nutritional status of the environment.
Soluble Aβ40 and Aβ42 peptides were observed elevated early, in cortex and hippocampus from
transgenic rats.
As
with transgenic mice, gene targeting is carried out in mouse embryonic stem cells (ES cells) derived from a very early (usually male) mouse embryo.
We are working on modeling of
transgenic fish, and some ecological models including various species of spiders and their webs.
Dolly the sheep was cloned, in fact, with the intention of eventually using this procedure to
create transgenic animals having useful properties, not as a means to make carbon copies of baseball legend Ted Williams or a favorite dead pet.
Alternative for Germany agrees with Donald Trump on climate change and with Greenpeace
on transgenic crops
Brian Ager, of the industry's Senior Advisory Group Biotechnology, says the delay will drive business to the US, where patents
for transgenic animals have been granted for some time.
RIKEN scientists and their collaborators tackled this issue by
developing transgenic strains of rice that are more resistant to drought.
Current research projects include: testing models of antagonistic coevolution by studying populations of nematodes that have evolved under different mating conditions; developing
transgenic technology in fruit flies in order to test hypotheses about the function of non-coding DNA (collaboration with Jack Bateman); and using mitochondrial genome sequences to investigate the coevolutionary relationships between follicle mites and their mammalian hosts.
In addition to having two ways to knock out target genes, other groups have reported advances in techniques to
produce transgenic rats as well as random knockouts that could be screened for interesting mutants.
Our strategy involved a 3 - month J147 treatment in huAPP / PS1
transgenic AD mice aged to 20 months, an age in which severe behavioral deficits and AD pathology manifest [10].
All of the new
transgenic rice varieties have one thing in common, however: they can only provide one particular micronutrient.
The permits, to grow two varieties of GM rice and one
transgenic corn strain, expired on 17 August.
The creatures were developed by scientists at the National University of Singapore as part of an ongoing attempt to
make transgenic fish that light up when exposed to such chemical toxins as PCBs, which are known to cause cancer in humans.
In fact, because the testing is fairly extensive and the quantities of
transgenic proteins in an engineered organism are typically so low, many scientists argue that it's easier to detect a potential allergen in a GM crop than in a conventional crop.
Lead researcher Gary W. Miller, PhD, professor and associate dean for research at the Rollins School of Public Health and his team
generated transgenic mice with increased levels of VMAT2 and found it led to an increase in dopamine release.
According to David Mortensen, professor of weed and applied plant ecology, Penn State, synthetic - auxin herbicides are usually used early in the growing season, but with the
new transgenic crop varieties coming on the market, these herbicides will be used later when temperatures are warmer and more plant species are leafed out.
To find out, the researchers fed four 2 - week old pigs pasteurized
transgenic milk and another group pasteurized regular milk for 16 days.
In this final installment, I'll provide a brief introduction as to how you can engineer new
transgenic flies to study your favorite gene (YFG).
As transgenic crops have spread around the world without the apocalyptic environmental consequences activists initially foretold, objections to the technology have shifted away from science.
A cloned beagle named Ruppy — short for Ruby Puppy — is the world's
first transgenic dog.
According to a report published today in the journal Nature, wild corn from the remote mountains of Oaxaca, Mexico contains
transgenic DNA.
Besides the low efficiency of cloning — just 1.7 per cent of embryos came to term — another challenge to creating
transgenic dogs is controlling where in the nuclear DNA a foreign gene lands.
«We already know how to produce
transgenic males that will yield sterile offspring,» Cator tells me.
a, c) McGill
APP transgenic rats exhibited lower recognition memory indices than wild type littermates at a) pre-plaque (3 months) and c) post-plaque (13 months) stages.
We welcome all attendees who are in the process of generating genetically - modified animals or who perform the experiments that follow to determine the corresponding phenotypes of
such transgenic animals.
Our Gene Targeting &
Transgenic Facility makes sophisticated gene targeting a turnkey service at a low cost.
Marker - assisted breeding is a conventional technique that allows breeders to track genes without using
transgenic approaches.
In contrast, hAPP mice had significant deficits (Table 1 and Figure 1E), as reported in this (18) and
other transgenic lines (19, 20).
Notably, the pattern of CSF peptides was similar at both time points and comparable to that observed in human CSF [50]; except for two observations: no Aβ37 was detected in the CSF of
McGill transgenic rats at any time point and the Aβ38 signal was as strong as the Aβ40 signal, under these conditions.
Characterisation of Insertion Sites in Rainbow Papaya — The First Commercialized
Transgenic Food Crop.
«New study refutes how fruit flies developed their tolerance for alcohol: Experiments use
transgenic organisms and biochemistry to test evolutionary hypothesis based on gene sequencing.»
Scientists are creating
transgenic mosquitoes with reduced ability to carry the devastating diseases that have plagued much of humanity.
Oakeshott S, Balci F, Filippov I, Murphy C, Port R, Connor D, Paintdakhi A, Lesauter J, Menalled L, Ramboz S, Kwak S, Howland D, Silver R, Brunner D. Circadian Abnormalities in Motor Activity in a
BAC Transgenic Mouse Model of Huntington's Disease.
Both companies, as well as seed firm Monsanto, based in St Louis, Missouri, are also working on
transgenic maize varieties, hoping to tap into a multibillion - dollar market (see Nature 466,548 - 551; 2010).
Phrases with «transgenic»