In the case of chronic diseases like hypertension, patients not sticking to their treatment plans is one of the main causes
of treatment failure.
More frequent causes of
treatment failure in canine demodicosis include poor pyoderma control, premature discontinuation of therapy, unsuccessful control of underlying conditions, and the use of concomitant glucocorticoids (Table 3).
Oddly though it was not found to relate to depression levels 4 weeks following
IVF treatment failure Verhaak et al. (2005a).
The KLK6 variants also independently predicted
treatment failure after surgery or radiation for prostate cancer in an independent cohort of 130 men from the International Cancer Genome Consortium (ICGC).
The KLK6 variants also independently
predicted treatment failure after surgery or radiation for prostate cancer in a Canadian cohort of men from the International Cancer Genome Consortium (ICGC).
Others, meanwhile, have theorized that
such treatment failures are due to the lack of a good GPS device: the car can go, they say, but it's not heading to the right address.
«We're now seeing
treatment failure rates to ACT of up to 30 % in western Cambodia and the Thai - Myanmar border,» reports Dr Elizabeth Ashley, Tracking Resistance to Artemisinin Collaboration (TRAC) Project Manager.
«Our results suggest that there are substantial differences between specific antipsychotic agents and between routes of administration concerning the risk of rehospitalization and
treatment failure among patients with schizophrenia,» the article concludes.
This is a desirable feature for a helper drug as it would reduce the risk of
treatment failure due to factors other than antibiotic resistance (e.g. biofilms, immunosuppression, etc.), allow dose reduction for toxic antibiotics such as colistin, and possibly even prevent selection of resistant mutants» says Guardabassi.
The rationale for an observational approach is to avoid the morbidity of lymphadenectomy (specifically to avoid the possibility of lymphedema) for two subsets of patients who never manifest isolated recurrence in the lymph node basin: those who have no melanoma remaining in the nodal basin and those who experience distant
treatment failure at or before the time of nodal recurrence.
If the response to treatment is poor then dietary modification is an option (
see treatment failure - below).
Insufficient information exists to conclude what the findings of the study would be if treatment dropouts were analysed
as treatment failures.
More frequent causes of
treatment failure include poor pyoderma control, premature discontinuation of therapy, unsuccessful control of underlying conditions, and the use of immunosuppressants such as glucocorticoids.
Cott described this as an «unparalleled achievement» in treating schizophrenics, because these patients had been
treatment failures through an extended program of different kinds of therapy.
«Public Health England will continue to monitor, and act on, the spread of antimicrobial resistance and potential
gonorrhoea treatment failures, to make sure they are identified and managed promptly.»
This study highlights that sofosbuvir with ribavirin and peginterferon should be considered for interferon - eligible GT - 3 patients, particularly for those with cirrhosis and / or
prior treatment failure,» said Graham Foster, Professor of Hepatology, Queen Marys University of London, UK.
Disease flare or exacerbation while on treatment in the setting of increased stress may not necessarily
reflect treatment failure.»
«It is only with more knowledge on antibiotic resistance dissemination — from the environment to pathogens in the clinic and leading to
antibiotic treatment failure rates — that we will be able to produce more sustainable antibiotic drugs,» Nesme says.
Identification of factors associated with viral suppression and
treatment failure when antiretroviral therapy is used for HIV prevention: results from the HIV Prevention Trials Network (HPTN 052) trial.
However, five participants in AQ - 13 group left the study or were lost to follow - up and two participants in the artemether / lumefantrine group had
late treatment failures with recurrence of their original infections.
«The goal of our research was to see if an objective measure like physical examination or imaging from an MRI could help predict
non-operative treatment failures in these professional pitchers,» commented Mark S. Schickendantz, MD the study's senior author from the Cleveland Clinic Sports Health Center in Cleveland, OH.
«We demonstrated that proactive drug monitoring is associated with better clinical outcomes, including
less treatment failure, serious infusion reactions, and less need for IBD - related surgery or hospitalization, when compared to reactive drug monitoring.»
Nationwide databases were linked to study the risk of rehospitalization and
treatment failure from 2006 to 2013 among all patients in Sweden with a schizophrenia diagnosis who were 16 to 64 years old in 2006.
The groups showed no significant differences in the number of
treatment failures requiring patients to take more medication, no difference in the number of asthma attacks and no difference in their need for emergency care.
The authors state, «It is important that clinicians be on high alert to recognize
gonorrhea treatment failures so that they can be reported promptly to public health officials.
There have been reports suggesting that elevations in vancomycin MIC values may be associated with
increased treatment failure and death, according to background information in the article.
A pilot study of definitive proton therapy (60 GyE in 15 fractions) for mucosal melanoma of the head and neck demonstrated a 3 - year survival rate of 58 % and
local treatment failure in only 1 of 14 patients, without unacceptable treatment toxicity.
They found no evidence of PPQ resistance, which suggests that DHA -
PPQ treatment failures are the result of artemisinin resistance.
«This model enhances the prognostic value of PET staging and response assessment, identifying a subset of patients with a very high risk of progression and
early treatment failure at 2 years.»
Treatment failures do occur and are often attributed to inadequate treatment of the environment, failure to treat all animals in the household, poor selection of products, and owner noncompliance.
Explain how partners collude with the narrative that leads to divorce, how healthy dissolution can be achieved, and how separation does not necessarily
imply treatment failure, but can, in fact, help each person move toward a healthy individual and family life.
Table 3: Reasons
for Treatment Failure in Dogs with Demodicosis All recognized Demodex mites in dogs appear to respond similarly to mite - targeted therapy.
Use of avoidance coping (Hynes et al., 1992) and escapist coping (Litt et al., 1992; Terry and Hynes, 1998) was linked to higher levels of depression following
IVF treatment failure, and was associated with infertility - specific stress pre-IVF treatment (Peterson et al., 2006a, b).
Prognostic factors and patterns of
treatment failure in dogs with unresectable differentiated thyroid carcinomas treated with megavoltage irradiation.
A recent phase III study revealed a benefit with pacritinib for patients with myelofibrosis and thrombocytopenia who have
experienced treatment failure with previous therapies.