Crowding of cerebellum is defined as the percentage of the volume of each part of the caudal cranial fossa (CCF) which is occupied by cerebellar parenchyma (Rostral Cerebellar CCF Percentage and Caudal Cerebellar CCF Percentage). (journals.plos.org)
When Jamie was first rescued by North Shore Animal League America as a young cat, she was quickly diagnosed with cerebella hyperplasia, a serious neurological problem that affects balance and mobility. (animalleague.org)
As the central nervous system is also a target of AAV vectors, Hélène Puccio and Patrick Aubourg's teams are investigating whether a similar approach using gene therapy could be as effective for the spinal cord and cerebellum as it is for the heart. (sciencedaily.com)