Definition of «fibril»

A fibril is a small, insoluble protein structure that resembles a hair-like or needle-shaped structure. Fibrils are typically found in amyloid proteins and can be associated with various diseases such as Alzheimer's disease, where the accumulation of amyloid-beta fibrils leads to the formation of plaques in the brain.

Phrases with «fibril»

Sentences with «fibril»

And although it may still be science fiction, he also believes that one day scientists may use the material properties of amyloid fibrils in research on invisible meta materials. (sciencedaily.com)
Products from an early stage of fibril formation were even more toxic to cells than the final, fibrillar form — just as some researchers suspect is the case for early stages of protein misfolding in Alzheimer's disease. (sciencemag.org)
Chris Dobson, a chemist and structural biologist at the University of Cambridge, U.K., suspected that a much broader range of proteins could form amyloid fibrils in test tubes. (sciencemag.org)
(see all sentences)