Definition of «methylation»

Methylation is a biochemical process in which a methyl group (CH3) is added to a molecule, typically DNA or RNA. This addition can have various effects on the function and activity of the target molecule, depending on where the methyl group is attached. In some cases, it can lead to changes in gene expression, while in other instances it may help protect genetic material from damage. Methylation plays an important role in many biological processes, including normal development, cellular differentiation and regulation of gene activity.

Sentences with «methylation»

  • At the same time the group was able to demonstrate that the reduced IGFBP2 secretion is accompanied by an increased rate of DNA methylation of various genes. (sciencedaily.com)
  • They also demonstrated that administration of a synthetic PPARα ligand to mouse dams during the perinatal period induces enhanced reductions in DNA methylation of fatty - acid β - oxidation genes in the liver of the offspring. (sciencedaily.com)
  • Changes in DNA methylation in brain cells has been an extremely active research area since these epigenetic changes were shown to alter the expression of genes needed to form and maintain long - term memories. (sciencedaily.com)
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