Definition of «misfolding»

"Misfolding" refers to a process in which a protein does not fold into its correct, three-dimensional shape. This can lead to functional impairments or even the formation of harmful protein aggregates in the body, potentially causing a variety of diseases.

Phrases with «misfolding»

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Sentences with «misfolding»

The patents also cover second and third generation GAIM - based therapeutic candidates currently in preclinical testing for other protein misfolding diseases of the central nervous system, including Alzheimer's, Parkinson's and tauopathies, and in peripheral amyloidoses. (proclarabio.com)
The polyphenol consituents of honey are suggested, by animal research, to have neuroprotective effects against free radical oxidation of delicate brain fats, misfolding of proteins, excitotoxicity, and inflammation. (kellybroganmd.com)
The broad applicability of the GAIM mechanism allows the Company to target a large number of protein misfolding diseases, including neurodegenerative and peripheral diseases. (proclarabio.com)
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