The term mutation refers to a change or alteration in the genetic makeup of an organism. This can occur naturally through various processes such as errors during DNA replication, exposure to radiation or certain chemicals, or it can be intentionally induced through techniques like gene editing. Mutations can result in changes to an organism's appearance, behavior, or physical abilities, and some mutations may have no noticeable effect at all. In general, the term "mutated" is used to describe any organism that has undergone a change in its genetic makeup.