The term "neoadjuvant" refers to a treatment that is administered before the primary therapy in an attempt to enhance its effectiveness. It can be used in various medical contexts, such as cancer treatments where chemotherapy or radiation therapy may be given before surgery to shrink a tumor and make it easier for surgeons to remove. The goal of neoadjuvant treatment is to improve the outcome of the primary therapy by preparing the body or targeting specific cells, making subsequent treatments more effective.