The term "ozone hole" refers to a significant depletion in the ozone layer, particularly over Antarctica during the southern hemisphere's spring. The ozone layer is a region in Earth's stratosphere that contains high concentrations of ozone (O3), which plays an important role in absorbing ultraviolet radiation from the sun and protecting life on earth. However, certain human-made chemicals called chlorofluorocarbons (CFCs) have been found to deplete the ozone layer when released into the atmosphere. During the Antarctic spring, cold temperatures cause a buildup of ozone-depleting substances in the stratosphere, leading to the formation of an "ozone hole." This phenomenon is not unique to Antarctica and can occur elsewhere, but it is most pronounced there due to the extreme cold. The depletion of the ozone layer has been shown to have negative impacts on human health, wildlife, and ecosystems, which is why efforts are being made globally to reduce CFC emissions and protect this vital part of Earth's atmosphere.