Definition of «polymerase»

Polymerase is an enzyme that plays a crucial role in DNA replication. It is responsible for synthesizing new strands of nucleic acids, such as RNA or DNA, by adding complementary nucleotides to an existing template strand. The process involves unwinding the double-stranded DNA and using one of the parental strands as a guide to create a new copy. Polymerase is essential for cell division and the transmission of genetic information from one generation to another.

Sentences with «polymerase»

  • The automated technique of polymerase chain reaction (PCR) is used to amplify polymorphic DNA fragments. (dnalc.org)
  • Methods: To identify proteins that modulate transcription, PNNL scientists expressed a tagged alpha - subunit of RNA polymerase in the bacterium Shewanella oneidensis under controlled growth conditions. (pnnl.gov)
  • 8 - oxo - dGTP can be utilized by DNA polymerases as a precursor for DNA synthesis, consequently, 8 - oxoG is incorporated into the nascent strand opposite adenine and cytosine in the template with almost equal efficiency, resulting in an A: T to C: G transversion of 8 - oxoG containing template DNA.» (mossnutrition.com)
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