Definition of «retinal dystrophy»

"Retinal dystrophy" refers to a group of genetic eye diseases that can cause damage to the retina, the tissue at the back of the eye that sends visual signals to the brain. These conditions can lead to vision loss and may cause problems with seeing in low light, color vision, and overall visual clarity.

Sentences with «retinal dystrophy»

Part 2 of this two - part article reviews lessons from Spark Therapeutics» pivotal program for Luxturna, a gene therapy approved for the treatment of patients with retinal dystrophy associated with confirmed biallelic mutation in the RPE65 gene, and summarize key considerations for the clinical development and commercialization of gene therapies. (lifescienceleader.com)
The progression of retinal dystrophy in the RCS rat is such that by 13 weeks post-graft most of the ONL has disappeared [33] and the photoreceptor outer segment layer is reduced to a debris zone [40], a finding we observed in dystrophic controls. (journals.plos.org)
Since the initial report the disease has also been described as having a progressive component leading to it also being called a hereditary retinal dystrophy [57]. (cgejournal.biomedcentral.com)
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