A significant amount of money refers to a large sum or quantity that holds importance, value and impact. It is an amount that can make a difference or have a substantial impact, and is typically more than just a small or moderate sum. The phrase can be used in various contexts, such as describing a large investment or donation, the value of an asset or property, a large prize or reward, and so on. The exact amount that constitutes a significant amount of money can vary depending on the context and circumstances, but it is generally understood to be a substantial amount that carries weight and impact.