"To set a destination" means to decide or determine where you want to go or what you want to achieve. It implies having a clear goal or purpose in mind.
Sentences with «to set a destination»
However, it could use further refinement in using apps to set destinations for navigation. (cnet.com)
If you're driving, though, you can also set a destination with the steering wheel mounted controls. (bestride.com)
The screen gave us some trouble when we tried to set a destination on the navigation system. (cnet.com)