Zoledronic is a medication that belongs to the class of drugs called bisphosphonates. It is used to treat and prevent certain types of bone loss, such as osteoporosis or Paget's disease. Zoledronic works by slowing down the breakdown of bone tissue, which helps to maintain strong bones and reduce the risk of fractures. The medication can be administered intravenously (IV) in a doctor’s office or hospital setting. It is also known by its generic name, zoledronic acid.