Noting that high estrogen concentrations are «a defining characteristic of dominant follicles,» Dr. Denis Magoffin (Ceders - Sinai Medical Center, Los Angeles, California, USA) and co-investigators examined whether abnormal expression of ERs could contribute to poor follicular development and ovulatory failure in women with PCOS. (bioidenticalhormones101.com)
Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta. (sciencedaily.com)
Using a combination of techniques, they found abnormal expression of more than a half - dozen myelin - related genes in the mental patients. (sciencemag.org)