For obvious reasons dogs with aggressive temperament are not the best choice for families with children. (dogtemperament.com)
Adult Dogs: Once a dog has assumed a dominance aggressive temperament it can be very difficult and sometimes impossible to change his outlook. (2ndchance.info)
Some of the mutations were in genes involved with brain development, which the researchers interpreted as relating to the less aggressive temperaments of dogs compared to wolves. (dogsnaturallymagazine.com)