A 2008 journal article on the development of allergic inflammation explains this systemic allergic response as: (wellnessmama.com)
A human enzyme that can degrade the chitin of insect exoskeletons also regulates allergic inflammation in asthma, reinforcing the similarities between immune responses to parasitic and allergic stimuli. (science.sciencemag.org)
«Without RORα, allergic inflammation went crazy in both our mouse models.» (sciencedaily.com)