Today, Maguire is on the scientific advisory board of Boston area — based Sage Therapeutics, which is testing a formulation of allopregnanolone called brexanolone. (sciencenews.org)
Dr. Lee's research has shown that certain synthetic analogs of allopregnanolone with improved half - life can stimulate chloride uptake in synaptoneurosomes, protect against bicuculline - induced seizures in alcohol - dependent rats, and reduce alcohol intake in alcohol preferring rats. (mcleanhospital.org)
Progesterone makes allopregnanolone in the brain, which interacts with GABA and serotonin for a foursome that truly soothes the female brain. (saragottfriedmd.com)