Phrases with «allosteric»

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"Allosteric" refers to the ability of a molecule or a compound to bind to a specific site on a protein or enzyme, which can then change the shape or activity of that protein or enzyme. This binding can either enhance or inhibit the protein's function. In simpler terms, allosteric describes how a molecule can act as a key to unlock or alter the behavior of a specific protein. Full definition

«allosteric» + noun

Sentences with «allosteric»

  • Together, our data suggest that clinical studies may be warranted to evaluate the therapeutic potential of ABL allosteric inhibitors and to determine whether combination therapies that incorporate these compounds are effective in treating metastatic breast cancer. (stke.sciencemag.org)
  • Administration of a positive allosteric modulator of the type 1 metabotropic glutamate receptors mGluR1 during the first postnatal week restored DA neuron excitatory synapse transmission and partially rescued the social preference defects, while optogenetic DA neuron stimulation was sufficient to enhance social preference. (inb.u-bordeaux2.fr)
  • Based on this work, the researchers identified a previously unknown regulatory mechanism in 2 - epimerase that involves direct interaction between one substrate molecule in the enzyme's active site and another in the enzyme's allosteric site. (sciencedaily.com)
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