Arginase enzymes maintain lower levels of free arginine in the blood and tissue. (bodybuilding.com)
In particular, fetal cells made high amounts of arginase - 2, an enzyme that breaks down L - arginine, a key ingredient in the production of a key messenger named tumor necrosis factor alpha (TNF - alpha). (sciencemag.org)
Blocking arginase using the small drug difluoromethylornithine (DFMO) before the start of symptoms in the mice, the scientists saw fewer CD11c microglia and plaques develop in their brains. (sciencedaily.com)