Type 1 diabetes mellitus (T1D) begins with autoimmune destruction of insulin producing cells in the pancreas, usually in children. (immunology.sciencemag.org)
In their new Stem Cells Translational Medicine study they show how this strategy can be safely applied to replace the pancreatic cells lost via autoimmune destruction in type 1 diabetes mellitus (T1D)[1]. (stemcellsportal.com)
The patients with high GAD antibody affinity displayed low insulin production, in keeping with advanced autoimmune destruction of the beta cells. (sciencedaily.com)