For instance, bigger canines apparently suffer from cancer more often, which could make sense; large dogs grow more than smaller breeds do, and cancer is rooted in abnormal cell growth. (mnn.com)
People frequently choose big canines however there are few that like having small dogs like fluffy as their pets. (usbones.com)
Big canines carry bigger loads on their joints and more weight causes more pressure. (bluebuffalo.com)