To me it's surprising but also revealing, as it tells us that if we want to manipulate or enhance blastema formation in a non-regenerative system we now have the key ingredients that have been favored during evolution as being critically important. (mdibl.org)
Primordia may synthetize a molecule that remains unknown and may promote or maintain blastema growth, the new tissue which is being regenerated. (sciencedaily.com)
Drs Benjamin L King and Voot P Yin at the MDI Biological Laboratory in Bar Harbor carried out a next - generation sequencing analysis into the genetics of these organisms to identify the genetics regulating blastema formation — the key step in regeneration in animals such as the zebrafish, axolotl and the bichir, where the injury site forms a mass of dedifferentiated cells that proliferate and differentiate in a coordinated manner to re-form the lost appendage. (mdibl.org)