I use it with other calming herbs and green tea to focus at work and I use it at night to calm down my mind and go to bed. (annmariegianni.com)
Sometimes this is accompanied by nausea, pain and / or diarrhea, so senna is often combined with calming herbs like fennel or ginger to help soften the blow, so to speak. (vitamin-insight.com)
If you do hit that second wind and need to come down, you can lower your cortisol levels and get your mind in sleep mode with mediation, prayer, peaceful music, adaptogen herbs like Rhodiola, Ashwaganda and Siberian Ginseng as well as calming herbs and minerals like Valerian Root and Magnesium. (mindbodygreen.com)