In the photo, the embryonic stem cell colonies are the rounded, dense masses of cells. (science.howstuffworks.com)
A single co-transfection of pooled Cas9 / gRNAs enabled isolation of cell colonies carrying simultaneous disruption of four genes with high efficiency. (journals.plos.org)
MSTN / PrP double mutations in cell colony make the target locus resistant to Van91I and Bsu36I treatment (arrowhead). (journals.plos.org)