Heterogeneity in human ES cultures is reflected by the variability in expression of cell surface antigens seen under culture conditions that promote stem cell renewal. (journals.plos.org)
Amongst the populations that expressed HIGH or MID levels of stem cell surface antigens, coexpression of transcripts for endoderm or mesoderm genes predominated, but in the LOW and NEG populations, there were significant numbers of cells expressing neural lineage markers, in particular Pax - 6 (Figure 3d). (journals.plos.org)
Levels of expression of pluripotency genes declined in parallel with the levels of stem cell surface antigens. (journals.plos.org)