To find out why, computational biologists came up with a computer model to predict how microbial metabolism and cellular composition change as cell size varies, using details about how much space a bacterium needs for its components — DNA, proteins, and the molecular factories called ribosomes — to function. (sciencemag.org)
Although many posit that tumor cell heterogeneity is of a genetic basis associated with inherent high genomic instability in tumor cells, the heterogeneous cellular composition in tumors has also been hypothesized, early on, to be the consequence of abnormal tumor stem cell differentiation (9). (cancerres.aacrjournals.org)
With DriverMap, Cellecta offers a novel, comprehensive end - to - end service portfolio for identifying differential gene expression, mapping of clinically actionable mutations in RNA, detecting cellular composition, and profiling immunotherapy targets. (cellecta.com)