It involves cell degradation of unnecessary or dysfunctional cellular components, which ensures cellular survival during starvation by maintaining cellular energy levels. (fitnessandpower.com)
That led Shaw and his team to a class of drugs called biguanides, which lower cellular energy levels by attacking the power stations of the cell, called mitochondria. (salk.edu)
SAN FRANCISCO, CA — A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria — the brain's cellular power plants — can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative disease. (gladstone.org)