The study's senior author, Amy S. Gladfelter of University of North Carolina, Chapel Hill, began this work as part of the HHMI / HCIA Summer Institute at the MBL, a group of 70 scientists who explored this emerging paradigm of cellular organization over five summers of intense, synergistic research. (sciencedaily.com)
The transition to compartmentalization and a eukaryotic cellular organization was facilitated by: (i) the ability to lipidate GTPases; (ii) the coupling of SNARE and longin domains; and (iii) the acquisition of dynamins and CopII - like coatamer proteins. (sciencedaily.com)
«We found that mitochondria communicate changes in cellular organization to initiate a specific metabolic reconfiguration that supports primitive hMSC properties,» said Dr. Teng Ma, senior author of the STEM CELLS study.. (sciencedaily.com)