Specifically, the data reveal distinct transitions in factors that influence the different cellular states including cell cycle regulators, transcription factors, and signaling factors. (sciencedaily.com)
Chemical modifications to DNA regulate cellular state and function. (nanoporetech.com)
The authors used a time - lapse video recording coupled to single - cell molecular analyses to study the process step - by - step and found that fate decision is not a unique programmed event, but the result of a very dynamic process composed of spontaneous fluctuation and selective stabilisation of alternative cellular states. (sciencedaily.com)