Yes, but possible interactions may occur with cimetidine, digoxin, fluorquinolone antibiotics (enrofloxacin,, marbofloxacin, orbifloxacin), phenytoin and tetracycline. (texaswestveterinarian.com)
Megaesophagus would be a condition where an antacid such as cimetidine could be helpful in mitigating injury to the esophagus though there is a trade off in protection against aspiration pneumonia. (marvistavet.com)
The effect of cimetidine on ACHN derived tumors was not statistically significant, as predicted. (elifesciences.org)