Our approaches include gene discovery, mapping of signaling networks in cell culture models and in vivo functional analyses done through gene knock - out and knock - in techniques in mice. (lerner.ccf.org)
Now, a team of researchers have created a new culture model of the human intestine where living tissue from a patient biopsy can be preserved and studied for days. (sciencedaily.com)
Developed primary culture models of activity - dependent gene transcription and of HD. (gladstone.org)