The Akt / mTORC1 axis was shown to promote the generation of Th1 and Th17 cells through downregulating suppressor of cytokine signaling protein 3 (15). (jimmunol.org)
As anticipated, since we are working with blood samples, the inflammatory and immune response categories with specific signaling pathway such as cytokines signaling between immune cells, IL - 6 and IL - 10 signaling were identified in our analysis. (journals.plos.org)
Cytokines signaling through receptors sharing the common gamma chain (gamma (c)-RRB-, including IL - 2, IL - 4, IL - 7, IL - 9, IL - 15 and IL - 21, are critical for the generation and peripheral homeostasis of B, T and NK cells. (science.institut-curie.org)