Cytosine methylation refers to the addition of a chemical mark called a methyl group to the DNA molecule at specific places. This process can influence how genes are expressed or regulated in a cell. Full definition
Furthermore, high - resolution analysis of cytosine methylation in primary and transformed cells has found less aberrant methylation of CpG island promoters in transformed cells than had been previously hypothesized based on candidate gene studies [58]. (journals.plos.org)
Our and previous findings suggest that both HDACs and cytosine methylation contribute to HIV - 1 latency, in agreement with a growing body of evidence demonstrating cooperation between these two gene silencing mechanisms [55], [56]. (journals.plos.org)
Citation: Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E (2009) Epigenetic Regulation of HIV - 1 Latency by Cytosine Methylation. (journals.plos.org)