Cytotoxic drugs are medicines that can kill or damage cells in the body. They are used to treat diseases like cancer by targeting and destroying cancer cells. Full definition
In laboratory experiments the researchers mimicked the way SOX9 is stabilised in brain tumour cells and showed that SOX9 turned on 40 to 50 genes in the tumour to make it more resistant to standard treatment with cytotoxic drugs and more prone to spread. (sciencedaily.com)
Conventional transplant conditioning employs radiation and / or high - dose cytotoxic drugs (also known as alkylators) to destroy the bone marrow and blood and immune cells; it also causes widespread cellular damage throughout the body. (sciencedaily.com)
It appears that, as the team expected, the test could be used to identify probable cytotoxic drugs. (sciencedaily.com)