EOS100850 potently rescues Th1 cytokine production in human whole blood treated by A2A agonists, and increased CD8 + T cell cytotoxicity in a co-culture assay of effector CD8 + T cells and target cancer cells (iteostherapeutics.com)
Research Paper In vitro single - strand DNA damage and cancer cell cytotoxicity effects of Temozolomide Shruti Purohit, Devashree Jahagirdar, Azad Kumar, Nilesh Kumar Sharma Oncomedicine 2017; 2: 102 - 110. (oncm.org)
Dsg3 CAAR - T cells exhibit specific cytotoxicity against cells expressing anti-Dsg3 BCRs in vitro and expand, persist, and specifically eliminate Dsg3 - specific B cells in vivo. (science.sciencemag.org)