Dacarbazine (DTIC), also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. (Wikipedia)(See all definitions)
Current treatments for melanoma patients include dacarbazine and temozolomide, which have an unsatisfactory response rate. (sciencedaily.com)
Combination chemotherapy, including dacarbazine, has helped some patients. (fcrsa.org)
However, Dr. Claudio Agostinelli recently found that increased CD68 + TAMs have again been implicated in poor outcomes in patients with negative fluorodeoxyglucose (FDG)- PET scans after two courses of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine).2 (hematology.org)