To achieve this, Crosnier and colleagues recently developed a method of expressing the entire ectodomains of functional recombinant Plasmodium proteins and used it to compile a large library of 42 proteins [27]. (malariajournal.biomedcentral.com)
Increasing evidence suggests that the synaptic functions of the amyloid precursor protein (APP), that is key to Alzheimer (AD) pathogenesis, may be carried out by its secreted ectodomain. (emboj.embopress.org)
This resource of extracellular P. falciparum merozoite proteins, which now contains 62 full - length ectodomains, will be a valuable tool in elucidating the function of these proteins during the blood stages of infection, and facilitate the comparative assessment of blood stage vaccine candidates. (malariajournal.biomedcentral.com)