The clots create «micro-necroses» at the leading edge of the tumor that over time probably fuse and create a big central necrosis. (emoryhealthsciblog.com)
In the local areas — the trophoblastic cells of the placenta and the edges of the tumor — both molecules were found at high concentrations. (scientificamerican.com)
She even found evidence that the devils» immune systems were occasionally performing this interferon - gamma trick themselves: In some instances, tumor cells near the edge of the tumor, in close proximity to white blood cells, showed MHC antigens that cells farther within the tumor mass lacked. (discovermagazine.com)