At least eight other epigenetic drugs are currently in different stages of development or human trials. (discovermagazine.com)
They applied epigenetic drugs and found that the numbers of T cells in the tumor increased. (uofmhealth.org)
The ultimate goal is to precisely understand the mechanisms of checkpoint blockade effectiveness and bring next generation, sustainable immunotherapies to even more patients, perhaps using by using epigenetic drugs in combination with checkpoint blockade to allow epigenetic reprogramming of exhausted T cells into durable and functional memory T cells. (sciencedaily.com)